internlm/Intern-S2-397B
Flagship scientific multimodal MoE (397B total / 17B active) on the Qwen3.5 hybrid linear/full-attention architecture — 262K context, MTP-accelerated reasoning. BF16 and FP8 checkpoints.
397B-A17B scientific multimodal MoE — FP8 on 8x H100/H200 per the official deployment guide
Guide
Overview
Intern-S2-397B is Shanghai
AI Laboratory's flagship multimodal foundation model for scientific
intelligence and long-horizon agents. It packs 397B total / 17B active
parameters across 512 experts on the Qwen3.5 MoE architecture
(Qwen3_5MoeForConditionalGeneration) with hybrid linear/full attention, a
262K context window, and a built-in shared-weight MTP head for speculative
decoding. An official FP8 checkpoint
(internlm/Intern-S2-397B-FP8)
halves the memory footprint and is the configuration the vendor validates.
Beyond chat and reasoning, it handles image and video inputs and improves agent capabilities for scientific workflows. Time-series inference exists but is currently LMDeploy-only (see Troubleshooting).
Prerequisites
- vLLM version: 0.22.1 or newer (per the official deployment guide)
- Hardware (FP8, recommended): 8x H100 or 8x H200
- Hardware (BF16): 8x H200 (141 GB each)
- Trust remote code: required — the repo ships a custom tokenizer
(
InternS1Tokenizer) - MoE kernel env: the deployment guide disables DeepGEMM
(
VLLM_USE_DEEP_GEMM=0, already set by this recipe) and selects the FlashInfer TRTLLM MoE backend on NVIDIA (applied automatically when you pick an NVIDIA GPU above)
Install vLLM
uv venv
source .venv/bin/activate
uv pip install -U "vllm>=0.22.1" --torch-backend=auto
Launch commands
Recommended — official FP8 checkpoint, TP=8
vllm serve internlm/Intern-S2-397B-FP8 \
--trust-remote-code \
--tensor-parallel-size 8 \
--reasoning-parser qwen3 \
--enable-auto-tool-choice \
--tool-call-parser qwen3_coder \
--mm-encoder-tp-mode data
BF16 (8x H200)
vllm serve internlm/Intern-S2-397B \
--trust-remote-code \
--tensor-parallel-size 8 \
--reasoning-parser qwen3 \
--enable-auto-tool-choice \
--tool-call-parser qwen3_coder \
--mm-encoder-tp-mode data
With MTP speculative decoding
vllm serve internlm/Intern-S2-397B-FP8 \
--trust-remote-code \
--tensor-parallel-size 8 \
--reasoning-parser qwen3 \
--enable-auto-tool-choice \
--tool-call-parser qwen3_coder \
--mm-encoder-tp-mode data \
--speculative-config '{"method":"mtp","num_speculative_tokens":3}'
Long-context (YaRN, up to ~1M)
The base config sets max_position_embeddings = 262144. For longer contexts,
turn on the Long Context feature above — it applies the deployment
guide's YaRN RoPE override (factor 4.0) and raises --max-model-len to
1,010,000. Static YaRN holds the scaling factor constant regardless of input
length, so leave it off unless you actually serve long prompts; for a ~524K
workload, halve the factor to 2.0.
Client Usage
Recommended sampling parameters from the model card:
from openai import OpenAI
client = OpenAI(api_key="EMPTY", base_url="http://localhost:8000/v1")
resp = client.chat.completions.create(
model="internlm/Intern-S2-397B-FP8",
messages=[{"role": "user", "content": "Design a synthesis route for paracetamol."}],
temperature=0.8,
top_p=0.95,
max_tokens=32768,
extra_body={
"top_k": 50,
"min_p": 0.0,
"spaces_between_special_tokens": False,
},
)
print(resp.choices[0].message.content)
Toggle thinking mode
Thinking is enabled by default. Disable it per request:
resp = client.chat.completions.create(
model="internlm/Intern-S2-397B-FP8",
messages=[{"role": "user", "content": "What is AGI?"}],
temperature=0.8,
top_p=0.95,
extra_body={"chat_template_kwargs": {"enable_thinking": False}},
)
The model card notes: do not disable thinking mode for agentic tasks.
Troubleshooting
- OOM at full 262K context: drop
--max-model-lento 65536 or 131072, or lower--gpu-memory-utilizationheadroom. - DeepGEMM warmup failures / slow startup: this recipe already exports
VLLM_DEEP_GEMM_WARMUP=skipandVLLM_USE_DEEP_GEMM=0per the deployment guide — if you launch outside the builder, set them yourself. - Time-series inputs (
time_series_url): currently supported only on LMDeploy, not vLLM — see the model card. - Wrong parser name: LMDeploy examples use
--tool-call-parser interns2-preview; on vLLM the correct parser isqwen3_coder(already wired into the Tool Calling feature above).